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Methods to reduce pain and improve healing after tonsil removal surgery

Clinical efficacy of platelet rich plasma and bupivacaine in pain and healing after tonsillectomy . A randomised control trial - Nil

Status
Active, not recruiting
Phases
Phase 2Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/03/105762
Enrollment
58
Registered
2026-03-10
Start date
Unknown
Completion date
Unknown
Last updated
2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: 8- Other Procedures

Interventions

Intervention1: Platelet rich plasma: Platelet rich plasma is a plasma fractions of patients own peripheral blood, which is infiltrated into tonsillar fossa / anterior tonsillar pillar immediately afte

Sponsors

Indira Gandhi Medical College shimla HP
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Recurrent sore throat, As per American Academy of Otolaryngology Head and Neck surgery; I. seven or more well-documented clinically significant , adequately treated sore throat in the preceding year, or II. five or more such episodes in each year of the preceding 2 years, or III. three or more such episodes in each of the preceding 3 years. Patient willing to give consent to participate

Exclusion criteria

Exclusion criteria: Allergic to bupivacaine 1. Current acute infection or peritonsillar abscess 2. History of palatine tonsils surgery or malignancy 3. Coagulopathy, bleeding disorder, thrombocytopenia 4. Other serious co-morbidity, anaemia, immunodeficiency, hypertensive, Chronic Renal Failure. 5.Patients on NSAIDS, anti-coagulants, anti-hypertensive drugs.

Design outcomes

Primary

MeasureTime frame
1.To evaluate post operative pain after platelet rich plasma and bupivacaine injection in tonsillar bed/anterior tonsillar pillar using Visual analogue score (VAS). 2. To evaluate wound healing between the platelet rich plasma and bupivacaine using a five grade scale based on percentage of slough coverage.Timepoint: Post operative Pain - Day 1 , day 3 , day 5 , Day 7 Healing - Day 1 , Day 3, Day 5 Day 7 and , Day 14

Secondary

MeasureTime frame
NilTimepoint: Nil

Countries

India

Contacts

Public ContactDr Jagdeep Thakur

Indira Gandhi Medical College shimla

anujagdeep@gmail.com9418477400

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Apr 4, 2026