Health Condition 1: J00-J99- Diseases of the respiratory system
Conditions
Interventions
Intervention1: Nil: Nil
Sponsors
Grant Medical Foundation Ruby Hall Clinic
Eligibility
Inclusion criteria
Inclusion criteria: 1 Patients with ARDS 2 Patients within 7 days from invasion or exacerbation of respiratory symptoms or acute onset of ARDS 3 Patients with bilateral opacities not fully explained by effusions 4 Patients with respiratory failure not fully explained by cardiac failure 5 PF ratio less than 300mmHg with PEEP at least 5cm H2O 6 ARDA diagnosis within 48 hours
Exclusion criteria
Exclusion criteria: 1 Patients with congestive cardiac failure 2 Patients with liver failure 3 Patients with chronic renal failure requiring renal dialysis therapy 4 Patients with burns more than 20 percent of total body surface area 5 Patients with chronic inflammatory or autoimmune disease 6 Pregnant or lactating women 7 Patients with palliative care
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of hyper inflammatory and hypo inflammatory phenotypes among ARDS patients admitted to ICUTimepoint: Number of ventilator free days within 28 days of ICU admission between the phenotypes Duration of ICU stay in days across the phenotype groups | — |
Secondary
| Measure | Time frame |
|---|---|
| ICU mortality in hyper inflammatory verses hypo inflammatoryTimepoint: Within 28days from ICU admission | — |
Countries
India
Contacts
Public ContactDr Kaustubh Zirpe
Grant Medical Foundation Ruby Hall Clinic
Outcome results
None listed