Skip to content

A new ultrasound method to monitor fluid overload in patients with severe infection

Prognostic role of VExLUS score in addressing fluid overload in sepsis patients in a tertiary care centre. - nil

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2026/03/105645
Enrollment
60
Registered
2026-03-09
Start date
Unknown
Completion date
Unknown
Last updated
2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: R688- Other general symptoms and signs

Interventions

Intervention1: Nil: Nil Intervention2: Nil: Nil Intervention3: Nil: Nil Intervention4: Nil: Nil Intervention5: Nil: Nil Intervention6: Nil: Nil

Sponsors

Government Thoothukudi Medical College
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Adult patients greater than 18 years old Life-threatening organ dysfunction Patients with diagnosis of sepsis confirmed by SIRS criteria

Exclusion criteria

Exclusion criteria: Refusal to participate Pregnant patients Patients already on hemodialysis Patients with previously known conditions that interfere with portal Doppler assessments, namely liver cirrhosis, or severe tricuspid regurgitation with structural heart disease. If any of these conditions are identified during the present episode, the patient would also be excluded. Age lesser than 18 years Hemodynamic instability due to active hemorrhage Poor echogenicity for ultrasound window Acute coronary syndrome

Design outcomes

Primary

MeasureTime frame
To evaluate the role of VExLUS score as a prognostic marker in septic patients thus providing greater sensitivity and earlier identification of fluid overload. This guides clinicians to decide on whether to administer supplemental fluid therapy or suspend its administrationTimepoint: At baseline and at discharge

Secondary

MeasureTime frame
to evaluate the possible relation between the different VExLUS grades & the adverse effects of intensive fluid administration & diuretic use & the need of thoracocentesis & paracentesis need for renal replacement therapy To Identify the possible association between higher VExLUS score & length of ICU stay & mortality Timepoint: At baseline & at discharge

Countries

India

Contacts

Public ContactVijayalakshmi

government thoothukudi medical college

aarvee93@gmail.com8903514505

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Apr 4, 2026