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Effect of High Intensity Exercise on Blood Glucose in Overweight and Obese Adults

High Intensity Interval Training on Overweight and Obese Individuals and its effect on Insulin Sensitivity: A Pre and Post Study. - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/03/105523
Enrollment
58
Registered
2026-03-06
Start date
Unknown
Completion date
Unknown
Last updated
2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: High Intensity Interval Training: HIIT Intervention Protocol The intervention will consist of a 8-week progressive HIIT program conducted 2 sessions per week (16 total sessions) under s

Sponsors

ICMR
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: - Adults aged 18-50 years - Body Mass Index (BMI) greater than or equal to 23 kg/m (overweight) or greater than or equal to 27 kg/m (obese) according to Extended International (IOTF) Body Mass Index Cut-Offs. - Sedentary lifestyle (any waking behavior characterized by an energy expenditure of 1.5 METs or less while in a sitting, reclining, or lying posture) (Physical Activity Guidelines Advisory Committee, 2018) - Ability to provide informed consent. - Medical clearance for high-intensity exercise participation.

Exclusion criteria

Exclusion criteria: Diagnosed cardiovascular disease, uncontrolled hypertension (greater than 160/100 mmHg), or cardiac arrhythmias - Type 1 diabetes mellitus or insulin-dependent Type 2 diabetes mellitus - Musculoskeletal injuries or conditions limiting exercise participation - Pregnancy or lactation - Current participation in structured exercise programs - Use of medications significantly affecting glucose metabolism (excluding stable doses of metformin) - Recent weight loss surgery (less than 12 months) or current enrollment in weight loss programs

Design outcomes

Primary

MeasureTime frame
Venous blood samples will be collected following a 12hr overnight fast at baseline and post-intervention Fasting Glucose levels will be analyzed using hexokinase method and Fasting Insulin levels will be analysed using Electrochemiluminiscence immunoassayTimepoint: screening anthropometric measurements body composition analysis Insulin Sensitivity Muscle mass will be recorded at Baseline week 0 visit 1 and post 48 hours Visit 2 Post intervention assessment similar to baseline procedures at Week 9

Secondary

MeasureTime frame
Anthropometric measurements: height, weight, BMI, waist circumference - Resting heart rate & blood pressure - Body fat percentage (via BIA InBody analysis) Timepoint: anthropometric measurements, resting heart rate & blood pressure will be recorded at Baseline week 0 visit 1 & post 48 hours Visit 2 Post intervention assessment similar to baseline procedures at Week 9

Countries

India

Contacts

Public ContactPrachitha D M

JSSAHER, Mysuru

anilbilimale@jssuni.edu.in9880709226

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Apr 4, 2026