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Which Medicine Controls Pain Better After Keyhole Surgery: Dexmedetomidine or Lidocaine?

Comparison Of The Effect of Intravenous Infusion of Dexmedetomidine And Lidocaine Intraoperatively On Postoperative Analgesia In Patients Undergoing Laparoscopic surgeries - Nil

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/03/105501
Enrollment
66
Registered
2026-03-06
Start date
Unknown
Completion date
Unknown
Last updated
2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K36- Other appendicitis

Interventions

Intervention1: Lidocaine infusion in group L: Patients will receive a loading dose of lidocaine 1.5 milligrams per kilogram over ten minutes followed by 2 milligram per kilogram per hour until the end

Sponsors

Shivani Meswani
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients with ASA grade 1 and 2 Patients scheduled for elective laparoscopic surgeries surgeries under general anesthesia Patients with no known allergy or contraindication to dexmedetomidine lidocaine or other study medications

Exclusion criteria

Exclusion criteria: Known hypersensitivity or allergy to dexmedetomidine lidocaine or any other component of the study drugs ASA grade 3 or above Severe hepatic renal or cardiovascular dysfunction History of arrhythmias conduction abnormalities or on antiarrhythmic medications Pregnant or lactating women History of chronic pain opioid use or regular analgesic intake within the past 48 hours Patients with neurological or psychiatric disorders that may interfere with pain perception or assessment Body mass index more than 35 Intraoperative conversion from laparoscopic to open surgery

Design outcomes

Primary

MeasureTime frame
Comparison of the effect of intravenous infusion of dexmedetomidine and lidocaine on postoperative analgesia in patients undergoing laparoscopic surgeriesTimepoint: Rescue analgesia at 30 min, 1 hour, 2 hours, 8 hours, 16 hours and 24 hours

Secondary

MeasureTime frame
NilTimepoint: Nil

Countries

India

Contacts

Public ContactDr Aparna Bagle

Dr. D.Y. Patil Medical College, Hospital and Research Centre

draparnabagle@gmail.com9422710943

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Apr 4, 2026