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A study comparing two methods to improve bone healing after lower wisdom tooth removal

A comparison of platelet rich plasma and synthetic graft with platelet rich plasma in bone regeneration of impacted mesioangular mandibular third molar extraction sites - Split mouth study - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/03/105483
Enrollment
34
Registered
2026-03-06
Start date
Unknown
Completion date
Unknown
Last updated
2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Platelet Rich Plasma: Placed in the extraction socket of impacted mandibular third molar immediately post surgery. Frequency : 1 time . Total duration : 6 months post surgery. Intervent

Sponsors

Dr Rangith
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients requiring the extraction of impacted bilateral mesioangular mandibular third molars. Adequate bone quality at the extraction site for grafting. Willingness to participate in the study and adhere to follow up visits. Medically healthy individuals with no contraindications to surgery.

Exclusion criteria

Exclusion criteria: Patients with systemic health issues(eg: uncontrolled diabetes, bleeding disorders). History of radiation therapy in the head and neck region. Active infections at the extraction site. Smokers or patients with poor oral hygiene. Pregnant or breast feeding women.

Design outcomes

Primary

MeasureTime frame
Bone regeneration evaluated by radiographic analysis(OPG) at follow-up at 6 months to assess bone density and new bone formation.Timepoint: 6 months post surgery

Secondary

MeasureTime frame
Soft tissue healingTimepoint: 1 week post surgery;Pain and SwellingTimepoint: 1 week and 1 month post surgery;Healing timeTimepoint: 1 week and 1 month post surgery;Complications like infection, graft failure, or delayed healingTimepoint: 1 week and 1 month post surgery

Countries

India

Contacts

Public ContactDr Rangith

Government Dental College, Kottayam, Kerala.

drpgantony@yahoo.com9447258110

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Apr 4, 2026