IV Propofol vs. Sevoflurane Gas for Laparoscopic Gallbladder Surgery: A Comparison of Patient Recovery and Vital Signs.

A STUDY TO COMPARE THE EFFICACY BETWEEN TOTAL INTRAVENOUS ANAESTHESIA WITH PROPOFOL AND BALANCED ANAESTHESIA WITH SEVOFLURANE IN TERMS OF RECOVERY PROFILE AND HEMODYNAMIC CHANGES DURING LARAROSCOPIC CHOLECYSTECTOMY- A RANDOMISED CONTROLLED STUDY - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/03/105428

Enrollment

Registered

2026-03-05

Start date

Unknown

Completion date

Unknown

Last updated

2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K801- Calculus of gallbladder with othercholecystitis

Interventions

Intervention1: Total intravenous anaesthesia with propofol Balanced anaesthesia with sevoflurane: Giving total intravenous anaesthesia with propofol in group A Balanced anaesthesia with sevoflurane in

Eligibility

Inclusion criteria

Inclusion criteria: Patients scheduled for elective laparoscopic cholecystectomy under general anaesthesia. Patients belonging to ASA Grade I, II, Patients aged between 20 and 50 years of either sex, Patient willing to give informed consent.

Exclusion criteria

Exclusion criteria: Patient refusal Heavy smoker (more than 20 cigarettes per day), patients having hemorrhagic disorders or patients with anticoagulant therapy, other systemic disorders, Patients on MAO-inhibitors, antidepressants and b-blockers, Patient had general anesthesia within the past 2 weeks Patients with history of allergy or sensitivity to volatile anesthetics or to propofol Patients with body mass index more than 1.5 times normal.

Design outcomes

Primary

Measure	Time frame
To compare post-operative recovery profile between patients receiving propofol versus sevoflurane following laparoscopic cholecystectomyTimepoint: After Extubation0 mins Eye opening time5-10 mins Time for following verbal commands5-10 mins Time for speaking name by patient5-10 mins Time to achieve modified Aldrete score5-10 mins	—

Secondary

Measure	Time frame
To compare the intra operative hemodynamic parameters, between propofol versus sevoflurane in patients undergoing laparoscopic cholecystectomy.Timepoint: intraop Baseline After intubation Before pneumoperitoneum After pneumoperitoneum 10mins 20mins 30mins Extubation	—

Countries

India

Contacts

Public ContactCHANDANA N P

Bangalore Medical College and Research Institute

bsrags@gmail.com9902360703

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Apr 4, 2026