Health Condition 1: K135- Oral submucous fibrosis
Conditions
Interventions
Intervention1: PRP AND iPRF: Platelet Rich Plasma is an autologous biological product obtained from the patients own blood that contains a high concentration of platelets suspended in plasma. Platelet
Sponsors
Rural Dental College Loni
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients clinically diagnosed with OSMF (Grade II to Grade III). 2. Age group between 18 60 years. 3. Patients with a history of areca nut or betel quid chewing. 4. Patients willing to give written informed consent and comply with follow-up visits.
Exclusion criteria
Exclusion criteria: 1. Patients with systemic diseases (e.g., diabetes mellitus, bleeding & clotting disorders). 2. Patients on anticoagulant or steroid therapy. 3. Pregnant or lactating women. 4. Patients with oral malignancy or other mucosal diseases. 5. Patients who had previously undergone treatment for oral submucous fibrosis 6. Patients with temporomandibular joint(TMJ) disorders that can cause trismus or any previous history of trauma to the TMJ.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Significant improvement in mouth opening and reduction in burning sensation. Better mucosal healing and elasticity compared to steroid therapy. Minimal or no adverse effects. Timepoint: every 2 months till 6th mouth | — |
Secondary
| Measure | Time frame |
|---|---|
| nilTimepoint: nil | — |
Countries
India
Contacts
Public ContactDr Anita Munde
Rural Dental College
Outcome results
None listed