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Does Exercise During Dialysis Improve Muscle Strength, Reduce Weakness, and Improve Treatment Effectiveness in Older Adults on Regular Dialysis?

Efficacy of A Structured Intradialytic Exercise Programme on Frailty, Sarcopenia and Dialysis Adequacy in Elderly Individuals Undergoing Maintenance Hemodialysis: A Randomized Controlled Trial - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/03/105408
Enrollment
50
Registered
2026-03-05
Start date
Unknown
Completion date
Unknown
Last updated
2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: N186- End stage renal disease

Interventions

Intervention1: Structured Intradialytic Exercise Programme: Patients in Exercise Training group will receive Intradialytic exercise training for three days a week on the day of dialysis for six weeks.

Sponsors

Dr Dinkey Mankad
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Age 65 85 years. Capability to perform physical fitness assessment tests or dynamometry. Sufficient musculoskeletal function to safely perform resistance or aerobic exercises (no severe joint deformities, contractures, or severe arthritis preventing exercise). An HD vintage more then 3 months and signing the consent form. No perfusion problems through an arteriovenous fistula to maintain adequate blood flow (250). No severe hemodialysis-related complications. Clinical and haemodynamic stable during the last 3 months. SARC-F score more then 4, indicating risk of sarcopenia.Screened and referred by a nephrologist to participate in an exercise program, based on screening for safety and medical suitability.

Exclusion criteria

Exclusion criteria: Acute infectious or other inflammatory illnesse Congestive heart failure, lung failure, severe liver disease, or active cancer Myocardial infarction or angina pectoris within the past 12 months. Pregnancy, kidney transplant within 6 months. Severe visual or hearing impairments that interfere with ability to follow exercise instructions or complete assessments. Inability to give informed consent. Severe cognitive and Neurological impairments (e.g., recent stroke with hemiparesis, severe Parkinson s disease)or diagnosed dementia that limits participation in physical activity or assessments. Patient having femoral fistula as access for HD. Hemodynamic instability (systolic blood pressure less then 90 mmHg or mean arterial pressure more then 60 mmHg) Those deemed unfit or denied clearance by the nephrologist will be excluded. All of the above exclusion criteria will be assessed and confirmed by a qualified nephrologist prior to enrolment.

Design outcomes

Primary

MeasureTime frame
Frailty stage based on the Fried phenotype. Sarcopenia according to the EWGSOP2 steps[European Working Group on Sarcopenia in Older People] Kt/V ratio Dialysis Adequacy.Timepoint: All outcomes will be assessed on Day 1 (baseline) and repeated after Week 6 of intervention.

Secondary

MeasureTime frame
KDQOL-36(Kidney Disease Quality of Life 36-Item Short Form)Timepoint: All outcomes will be assessed on Day 1 (baseline) and repeated after Week 6 of intervention.

Countries

India

Contacts

Public ContactDr. Niketa Patel

College of Physiotherapy, Sumandeep Vidyapeeth Deemed To Be University, Vadodara

niketagautam@gmail.com9099774190

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Apr 4, 2026