A study comparing two drugs to prevent an increase in blood pressure and heart rate during breathing tube placement under anesthesia

A Comparative study between IV Magnesium Sulphate and Dexmedetomidine for attenuation of haemodynamic pressor response during Laryngoscopy and Endotracheal intubation - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/03/105357

Enrollment

120

Registered

2026-03-05

Start date

Unknown

Completion date

Unknown

Last updated

2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: Z018- Encounter for other specified special examinations

Interventions

Intervention1: Dexmedetomidine: Injection Dexmedetomidine Dose:1 microgram/kg body weight Route of Administration: Intravenous infusion Dilution: Diluted in 100 ml of 0.9% Normal Saline Duration of Ad

Eligibility

Inclusion criteria

Inclusion criteria: a. Patients aged 18 60 years. b. ASA I & II, Mallampatti grade I & II. c. Elective non-cardiac surgery under GA.

Exclusion criteria

Exclusion criteria: a. Allergy to study drugs. b. Anticipated difficult intubation. c. Pregnancy and lactation. d. Morbid obesity. e. Cardiorespiratory, renal, hepatic illness. f. Diabetes mellitus. g. HR lesser than 60 bpm, SBP lesser than 100 mmHg.

Design outcomes

Primary

Measure	Time frame
Change in Heart Rate, Systolic Blood Pressure, Diastolic Blood Pressure, Mean Arterial PressureTimepoint: Change in Heart Rate, Systolic Blood Pressure, Diastolic Blood Pressure, Mean Arterial Pressure	—

Secondary

Measure	Time frame
NilTimepoint: Nil	—

Countries

India

Contacts

Public ContactDr Rama Kant

Pacific Medical College and Hospital

dr.rkbhu1@gmail.com8058021697

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Apr 4, 2026