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A Study to Compare Two Ayurvedic Herbal Applications (Vatankur-Masoor and Manjishtha-Madhu) Lepa in the Treatment of Facial Dark Patches Mukha Vaivarnya (Vyanga)

Comparative Clinical Study To Evaluate The Efficacy of Vatankur Masoor Lepa with Manjishtha Madhu Lepa in the management of Mukhagat Vaivarnya - Nil

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/03/105343
Enrollment
80
Registered
2026-03-05
Start date
Unknown
Completion date
Unknown
Last updated
2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: L814- Other melanin hyperpigmentation

Interventions

None listed

Sponsors

Vidarbha Ayurved Mahavidyalaya Amravati
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Patients in the age group of 20- 50 years,irrespective of their gender,religion,economic status ,marietal status. 2.Patient of vyanga with chronicity less than 5 years. 3.Patient of vyanga having symptoms of Shyava Varna Yukta,(Hyperpigmentation) Niruja, Tanu Mandalas present over the face. 4.Stable melasma(no procedure-based treatments in prior 3 months;no new topical depigmentants in prior 4 weeks. 5.Willing to avoid other depigmenting agents and to adhere to photoprotection advice. 6.Able to provide written informed consent.

Exclusion criteria

Exclusion criteria: 1.Age less than 20 years and more than 50 years 2.Pregnancy or lactation; planning pregnancy within study period. 3. Active facial dermatoses (e.g., acne with inflammatory lesions, dermatitis) that may confound assessment. 4. History of any Hypersensitivity to any study ingredients (perform patch test). 5. Systemic retinoids in prior 6 months; topical retinoids, hydroquinone, corticosteroids, chemical peels, or laser therapy in prior 4 8 weeks. 6. Significant hepatic/renal disease or immunosuppression. 7. Participation in another interventional trial within 30 days. 8. Congenital melasma (patches over face since birth) 9.Having viral infection like herpes 10.Patient having systemic diseases like HTN,DM,Thyroid Disorder 11.Inflammatory Pigmentation 12. Past and present history of skin disease like psoariasis, vitiligo, person suffering any bacterial and fungal infection or any skin infection or under medication with antibiotics and anti fungals.

Design outcomes

Primary

MeasureTime frame
Assessment of mukha vaivarnya after applying lepa will be done according to subjective criteria . Subjective criteria as following 1.Shyavata 2.Parush Sparsh 3.Daha 4.Kandu Within 42 to 63 days of follow upTimepoint: 0th day,7th day,14th day,21st day,28th day,35th day,42nd day,49th day,56th day,63rd day

Secondary

MeasureTime frame
Remission from all kind of vaivarnya(vyanga) Healthy skin establishedTimepoint: 49th day,56th day,63rd day

Countries

India

Contacts

Public ContactDrPunam Nandkishor Patil

Vidarbha Ayurved Mahavidyalaya, Amravati.

skchopkar@gmail.com9423105104

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Apr 4, 2026