Health Condition 1: K053- Chronic periodontitis
Conditions
Interventions
Intervention1: Nil: Nil
Intervention2: Nil: Nil
Intervention3: Nil: Nil
Sponsors
DR KIRUBAVATHI
Eligibility
Inclusion criteria
Inclusion criteria: Group 1: Systemically And Periodontally Healthy Age 18 Years And Above Good Systemic Health At Least 20 Natural Teeth Excluding Third Molars (Minimum 10 Pairs Of Antagonistic Teeth) Full Mouth Plaque Score 20 Percent Or Less Full Mouth Bleeding Score 10 Percent Or Less Probing Pocket Depth 3mm Or Less No Clinical Attachment Loss Group 2: Systemically Healthy With Generalized Stage iii/iv Periodontitis age 18 years and above at least 20 natural teeth excluding third molars (minimum 10 pairs of antagonistic teeth) full mouth plaque score more than 20 percent full mouth bleeding score more than 10 percent probing pocket depth 6 mm or more clinical attachment loss 5 mm or more radiographic bone loss extending to the middle or apical third of the root group 3: generalized stage iii/iv periodontitis with uncontrolled type 2 diabetes mellitus age 18 years and above probing pocket depth 6 mm or more clinical attachment loss 5 mm or More Full Mouth Plaque Score More Than 20 Percent Full Mouth Bleeding Score More Than 10 Percent Tooth Loss Due To Periodontitis Five Teeth Or More Radiographic Evidence Of Bone Loss Type 2 Diabetes Mellitus On Oral Hypoglycemic Drugs For At Least One Year With Hba1c Between Eight And Ten Percent Group 4: Periodontally Healthy With Type 2 Diabetes Mellitus Age 18 Years And Above At Least 20 Natural Teeth Excluding Third Molars Full Mouth Plaque Score 20 Percent Or Less Full Mouth Bleeding Score 10 Percent Or Less Probing Pocket Depth 3mm Or Less No Clinical Attachment Loss Type 2 Diabetes Mellitus On Oral Hypoglycemic Drugs For At Least One Year With Hba1c Seven Percent Or Less
Exclusion criteria
Exclusion criteria: 1.Patients under Immunosuppressants and or antibiotics and or anti- inflammatory medications and or any drugs that could influence the periodontium for the past 6 months. 2.Pregnant or lactating mothers 3.Current and past smokers 4.Previous history of periodontal or orthodontic therapy. 5.Those receiving iron replacement therapy for anemia. patients with uncontrolled diabetes mellitus with hba1c more than ten patients with a history of any systemic disease other than type 2 diabetes mellitus and diabetic individuals with a history of diabetic complications, those under insulin therapy, and those with hba1c more than ten were excluded subjects not willing to participate or not willing to give informed consent
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To evaluate the serum and salivary PGLYRP1 levels in patients with generalized stage III/IV periodontitis with and without type 2 diabetes mellitus. 2. To compare and correlate the serum and salivary PGLYRP 1 level in patients with generalized stage III/IV periodontitis with and without type 2 diabetes mellitus.Timepoint: Baseline | — |
Secondary
| Measure | Time frame |
|---|---|
| To correlate the serum and salivary levels of PGLYRP 1 with the clinical parameters in generalized stage III/IV periodontitis with and without type 2 diabetes mellitus. 2. To evaluate the diagnostic accuracy of these biomarkers to discriminate between periodontal health and disease using ROC.Timepoint: Baseline | — |
Countries
India
Contacts
Public ContactKIRUBAVATHI S
SRM DENTAL COLLEGE
Outcome results
None listed