None listed
Conditions
Interventions
Intervention1: Nebulization of Dexmedetomidine 1 mcg/kg + 0.9% NS: Single dose of 5ml Nebulization of Dexmedetomidine 1mcg/kg + 0.9% NS over 10 minutes, 20 minutes prior to surgery
Control Interventio
Sponsors
Dr Harshith P Gowda
Eligibility
Inclusion criteria
Inclusion criteria: After taking informed written consent, patients aged between 18 and 60 years, American Society of Anesthesiologists class I and II, with a normal airway, undergoing elective surgery under general anesthesia with endotracheal intubation were included in the study
Exclusion criteria
Exclusion criteria: Patient s refusal, emergency surgeries, obese individuals with BMI more than 30kg/m2, Mallampati grading more than 2, anticipated difficult intubation requiring more than 15 seconds for intubation or more than two attempts at laryngoscopy, patients with allergy to Dexmedetomidine, taking medicines that affect the heart rate such as Beta blockers, Clonidine, Gabapentin, Pregabalin and pregnant patients are excluded from the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To evaluate the effects of preoperative nebulized Dexmedetomidine (1mcg/kg) and nebulized Lignocaine 4% (3mg/kg) on the hemodynamic response to Pneumoperitoneum by monitoring Heart rate (HR) Blood pressure response which includes: Systolic blood pressure (SBP) Diastolic blood pressure (DBP) Mean arterial blood pressure (MAP). Timepoint: Baseline (T0), at 15 minutes(P0), and at 16 minute (P1), 18 minutes (P3), 20 minutes (P5) and 30 minutes (P10) | — |
Secondary
| Measure | Time frame |
|---|---|
| Total intraoperative INJ Fentanyl consumptionTimepoint: Baseline (T0), At 15 minutes (P0) & at 16 minute (P1), 18 minutes (P3), 20 minutes (P5), & 30 minutes (P10). | — |
Countries
India
Contacts
Public ContactDr Mithali V
BGS Global Institute of Medical Science
Outcome results
None listed