Health Condition 1: K053- Chronic periodontitis Health Condition 2: E119- Type 2 diabetes mellitus without complications
Conditions
Interventions
Intervention1: Nil: Nil
Intervention2: Nil: Nil
Intervention3: Nil: Nil
Control Intervention1: NIL: NIL
Sponsors
Bernice Miraclyn
Eligibility
Inclusion criteria
Inclusion criteria: Adult males or females with healthy periodontium and with no systemic conditions Adult males or females with a diagnosis of type 2 diabetes mellitus and periodontitis Diabetes defined as those patients diagnosed with type 2 diabetes mellitus and are on oral hypoglycemic drugs for past one year with HbA1c lesser than equal to 10% Periodontitis defined as those patients with periodontal probing pocket depth greater than or equal to 6mm,clinical attachment loss greater than or equal to 5mm,full mouth plaque score greater than 20%,full mouth bleeding score greater than 10% with radiographic evidence of bone loss extending to middle or apical third of the root with at least 20 natural teeth excluding third molars
Exclusion criteria
Exclusion criteria: Patients under immunosuppressants and or antibiotics and or anti inflammatory medications and or any drugs that could influence the periodontium for the past 6 months. Pregnant or lactating mothers. Current and past smokers. Previous history of periodontal or orthodontic therapy. Patients with Uncontrolled diabetes mellitus with HbA1c greater than 10 percent. Patients with a history of any other systemic disease other than type 2 diabetes mellitus. Those diabetic individuals giving a history of diabetic complications and those under insulin therapy were excluded. Subjects not willing to participate and not willing to give consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Evaluating the role of chitotriosidase and activin-a in the saliva and serum of generalised stage iii/iv periodontitis with and without type 2 diabetes mellitus will further enhance our knowledge on the underlying mechanisms mediating inflammation in periodontitis and in type 2 diabetes associated periodontitisTimepoint: baseline | — |
Secondary
| Measure | Time frame |
|---|---|
| NILTimepoint: NIL | — |
Countries
India
Contacts
Public ContactDr Devapriya Appukuttan
SRM Dental College Ramapuram
Outcome results
None listed