A study to compare the stability of dental implants placed immediately after tooth removal, with and without the use of platelet-rich fibrin, in healthy patients

EVALUATION OF SECONDARY STABILITY OF IMMEDIATELY PLACED SLA IMPLANTS WITH AND WITHOUT I-PRF IN SYSTEMICALLY HEALTHY PATIENTS A SINGLE BLINDED RANDOMISED CONTROLLED CLINICAL STUDY - nil

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/03/105284

Enrollment

Registered

2026-03-03

Start date

Unknown

Completion date

Unknown

Last updated

2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Injectable Platelet Rich Fibrin: I-PRF in this study will be used by wetting the Implant surface. Studies have shown that by wetting the implant surface, the hydrophilicity increases th

Eligibility

Inclusion criteria

Inclusion criteria: Single-rooted tooth in single or multiple edentulous site in maxillary and mandibular arch. Systemically healthy patients. Tooth loss due to trauma, grossly decayed, failed root canal treatment without periapical pathology, and any other teeth with healthy bone that can be removed atraumatically. Age between 25 and 60 years.

Exclusion criteria

Exclusion criteria: Multirooted teeth. Medically compromised patients such as diabetics, on bisphosphonates, hormone replacement therapy, Etc. Known allergy to any material or medication used in the study. Any Previous History of head and neck radiation therapy. Chemotherapy in the last 12 months. Severe psychologic problems. Pregnancy or lactation. Tooth loss due to periodontitis. Age above 60 years. Age below 25 years. Patient not willing to sign the consent approved by the Human Studies Committee.

Design outcomes

Primary

Measure	Time frame
The primary clinical outcome variable is evaluated based on the secondary stability with and without I-PRF, and the power analysis will be based on this variable. The current study s power analysis is based on the calculations of the primary outcome variable obtained from the key article.Timepoint: baseline, 2 weeks, 4 weeks, 8 weeks, 12, weeks, 16 weeks	—

Secondary

Measure	Time frame
The secondary clinical outcome measures are Changes in Crestal bone level changes, primary stability,wound healing index, papillary height changes, visual analog scale for pain assessment.Timepoint: baseline, 2 weeks, 4 weeks, 8 weeks, 12, weeks, 16 weeks	—

Countries

India

Contacts

Public ContactHarinath P

SRM Dental College

hari_feb14@hotmail.com9840482400

Outcome results