The study compares two antimicrobial gels used along with deep cleaning in patients with gum disease

A comparative evaluation of oxygen releasing formula and chlorhexidine gel as an adjunct to scaling and root planing in the management of patients with stage II grade A periodontitis. A clinico microbiology study. - NIL

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/03/105269

Enrollment

Registered

2026-03-03

Start date

Unknown

Completion date

Unknown

Last updated

2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis

Interventions

Intervention1: Oxygen releasing gel: Evaluation of Oxygen releasing gel as a local drug delivery agent clinically and micro biologically in patients with Stage II Grade A periodontitis after scaling a

Eligibility

Inclusion criteria

Inclusion criteria: 1. Subjects with Stage II grade A periodontitis. 2. Probing pocket depth less than or equal to 5mm, with minimal bone loss in the past five years. 3. Subjects with a minimum of 20 teeth and at least two periodontal pockets. 4. Subjects with clinical attachment loss of 3 to 4mm.

Exclusion criteria

Exclusion criteria: 1. Prior or current antibiotic therapy. 2. Medication inducing gingival enlargement. 3. Pregnant or lactating women. 4. Subjects with the habit of tobacco chewing and smoking. 5. Immunocompromised subjects. 6. Subjects with any systemic diseases.

Design outcomes

Primary

Measure	Time frame
Reduction of clinical signs like Gingival index, Modified sulcus bleeding index, probing pocket depth and Clinical attachment level.Timepoint: 0 and 30th day	—

Secondary

Measure	Time frame
Reduction in colony forming units of Porphyromonas gingivalis and Aggregatibacter actinomycetemcomitans.Timepoint: 0 and 30th day	—

Countries

India

Contacts

Public ContactVivekananda M R

Sri Hasanamba dental college and hospital

vivekcodsperio@gmail.com9980843531

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Apr 4, 2026