Health Condition 1: J441- Chronic obstructive pulmonary disease with (acute) exacerbation
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Adults more than or equal to 18 years old with AECOPD will be considered. Presence of not fully reversible airflow limitation, with an FEV1/ FVC less than 0.7 post bronchodilation measured by spirometry. COPD patients, GOLD stage II-IV Patients who are hospitalised for severe exacerbation of COPD experiencing worsening of dyspnoea, cough, and or sputum lasting up to 14 days, often accompanied by tachypnoea and tachycardia for duration less than 2 weeks. Significant Sputum production.
Exclusion criteria
Exclusion criteria: Patients that had under gone previous lung transplantation, required mechanical non-invasive ventilation for more than eight hours per day, had history of haemoptysis or pneumothorax in the last 12 months, were pregnant or breastfeeding. Severe cardiac comorbidities (recent heart attack, unstable angina, uncontrolled rhythm disorders, and unstable cardiac failure) or neuromuscular disorders. Patients who present with Asthma and Asthma-COPD overlap syndrome ACOS. Patients who present with other respiratory conditions such as bronchiectasis, cystic fibrosis and interstitial lung diseases.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| sputum clearance dyspnea peak cough flowTimepoint: baseline and after 14 days intervention | — |
Secondary
| Measure | Time frame |
|---|---|
| pulmonary function arterial blood gases levels functional capacity health related quality of life anxiety and depressionTimepoint: baseline and after 14 days intervention | — |
Countries
India
Contacts
Jamia Millia Islamia