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Effect of Ondansetron on Preventing Blood Pressure Drop During Spinal Anesthesia for Cesarean Birth.

Effectiveness of Prophylactic Ondansetron for Preventing Spinal Anesthesia-Induced Hypotension in Pregnant Patients Undergoing Elective Lower Segment Cesarean Section: A Prospective Randomized Study - nil

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/03/105241
Enrollment
50
Registered
2026-03-02
Start date
Unknown
Completion date
Unknown
Last updated
2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O295- Other complications of spinal andepidural anesthesia during pregnancy

Interventions

Intervention1: Group-B: Inj Ondansetron 6mg: Patients will receive intravenous ondansetron 3ml just before giving spinal anesthesia Each ml contains 2mg of ondansetron Making it a total of 6mg Con

Sponsors

Dr Suchith R
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA grade 2 parturients who are primigravida patients aged between 18 to 30 years who are udergoing Elective LSCS under spinal anaesthesia

Exclusion criteria

Exclusion criteria: 1.Patient refusal. 2.Patient history of allergy to local anaesthetic. 3.Patient with bleeding diathesis. 4. Patients with severe cardiovascular diseases with QT prolongation 5. Pre eclamptic and gestational hypertensive patients on anti-hypertensive medications. 6. Patient having neurological disorders. 7. Patient with spine abnormalities 8. Local site infection.

Design outcomes

Primary

MeasureTime frame
To evaluate the effectiveness of prophylactic IV ondansetron in preventing spinal anesthesia induced hypotension during elective LSCS.Timepoint: to note intra op vitals at 0, 5 ,10,15,30 minutes

Secondary

MeasureTime frame
Timepoint: ;o assess sensory block level To measure total ephedrine requirement To compare neonatal APGAR scores at 1 and 5 minutes To evaluate other adverse effects (nausea, vomiting, shivering, bradycardia)Timepoint: To note intra op vitals at 0, 5 ,10,15,30 minutes

Countries

India

Contacts

Public ContactDr Suchith R

Rajarajeswari Medical College Hospital Bangalore

drgskarthik@gmail.com9538220515

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Apr 4, 2026