Health Condition 1: 7- Osteopathic
Conditions
Interventions
Intervention1: Multimodal delirium prevention bundle: Preoperative Phase
Ultrasound-guided Pericapsular Nerve Group (PENG) block under aseptic precautions using
0.2 percent ropivacaine at 0.5 mL per k
Sponsors
Multidisciplinary Research UnitDepartment of health researchGovernment of India
Eligibility
Inclusion criteria
Inclusion criteria: ASA Physical Status II to IV Radiologically confirmed proximal femoral fracture Planned surgery within 48 hours of trauma Informed consent from patient or legally authorised representative
Exclusion criteria
Exclusion criteria: Documented dementia or MMSE less than 20 Major psychiatric illness or substance abuse Chronic opioid use of more than 30 morphine milligram equivalents per month) Refusal or contraindication to regional anaesthesia Severe hepatic or renal failure Preoperative delirium
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare the incidence of postoperative delirium between the multimodal intervention group and the standard care groupTimepoint: 0 hours,12 hours,24 hours,36 hours,48 hours, 72 hours postoperative period. | — |
Secondary
| Measure | Time frame |
|---|---|
| To compare severity and duration of deliriumTimepoint: 0 hours,12 hours,24 hours,36 hours,48 hours, 72 hours postoperative period.;Numeric rating scale pain scoresTimepoint: every six hours in the postoperative period for 48 hours;Total opioid consumptionTimepoint: 24 hours,48 hours,72 hours;Biomarker trends in CRP, IL-6, S100BTimepoint: baseline.24 hours, 48 hours, 72 hours postoperative | — |
Countries
India
Contacts
Public ContactShibani Padhy
Nizams Institute of medical sciences
Outcome results
None listed