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A Study on Different Doses of Magnesium for Improving Pain Relief After Abdominal Hysterectomy

COMPARISION OF DIFFERENT DOSES OF MAGNESIUM SULPHATE AS AN ADJUVANT TO LEVOBUPIVACAINE IN ULTRASOUND GUIDED TRANSVERSUS ABDOMINIS PLANE BLOCK IN PATIENTS UNDERGOING TOTAL ABDOMINAL HYSTERECTOMY UNDER SPINAL ANAESTHESIA: A PROSPECTIVE RANDOMISED STUDY - NIL

Status
Active, not recruiting
Phases
Phase 2Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/03/105204
Enrollment
60
Registered
2026-03-02
Start date
Unknown
Completion date
Unknown
Last updated
2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O00-O9A- Pregnancy, childbirth and the puerperium

Interventions

Intervention1: Group A: USG guided transversus abdominis plane block with 20 ml of 0.25% Levobupivacaine with 150mg of Magnesium Sulphate Constituted in 3ml of Normal Saline on either side. Control

Sponsors

Harshith Ananth
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Undergoing Total abdominal hysterectomy (TAH) under spinal anesthesia

Exclusion criteria

Exclusion criteria: 1.Patient refusal. 2.Patients belonging to ASA 3 and above 3.Patients having history of allergy to local anaesthetics. 4.Patient with bleeding diathesis/deranged coagulation profile 5.Patient suffering from neurological and psychiatric disorders. 6.Patient having spine abnormalities. 7.Local site infection.

Design outcomes

Primary

MeasureTime frame
To compare VAS scores between both the groups in the post operative period. Timepoint: To compare VAS scores between both the groups at 0min,30min,1hr,2hrs,4hrs,6hrs,8hrs ,16hrs and 24hrs

Secondary

MeasureTime frame
1.Number of doses of rescue analgesic used 2.Time to first rescue analgesic 3.Time taken for regression of sensory level up to T8 dermatome 4.Adverse effects if any. Timepoint: Time of first rescue analgesia within first 24 hours

Countries

India

Contacts

Public ContactDr Sudheer R

Rajarajeswari Medical College And Hospital

sudheer_mys@yahoo.co.in9741117754

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Apr 4, 2026