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Effect Of Platelet Rich Plasma Injection In Patients With Early And Moderate Knee Arthritis.

Efficacy Of Platelet Rich Plasma (PRP) In Kellgren And Lawrence Grades 2-3 Osteoarthritis Of Knee Joint In Patients Attending a Tertiary Care Hospital In Kolkata. - Nil

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/03/105105
Enrollment
50
Registered
2026-03-02
Start date
Unknown
Completion date
Unknown
Last updated
2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M171- Unilateral primary osteoarthritisof knee

Interventions

Intervention1: Platelet Rich Plasma (PRP) In Knee Osteoarthritis: Functional Analysis After Giving Injection Prp In Kellgren And Lawrence Grades 2,3 Knee Osteoarthritis Control Intervention1: Not Appl

Sponsors

RG Kar Medical College And Hospital
Lead Sponsor
PROF Dr SANJAY KUMAR
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: 1.Diagnosed with knee osteoarthritis (Kellgren-Lawrence grade II or lI) 2. Presence of chronic knee pain for at least 3 months 3.Able and willing to provide informed consent 4.Willing to undergo intra-articular PRP injection and adhere to follow-up protocol 5. Seronegative Adults 6. Patients with Unilateral or Bilateral knee oA of grades 2-3 (KL classification) ; For B/L OA, the more symptomatic knee (acc. To VAS Score) will be selected, C/L knee must not have undergone PRP or intraarticular steroid injection in last 3 months.

Exclusion criteria

Exclusion criteria: 1.Advanced osteoarthritis (Kellgren-Lawrence grade 4) 2.History of inflammatory joint diseases (e.g., rheumatoid arthritis, gout) 3.Recent knee trauma or surgery within the past 6 months 4.Active joint infection or systemic infection

Design outcomes

Primary

MeasureTime frame
Change in total WOMAC(Western Ontario and McMaster Universities Osteoarthritis Index) score from baseline to 6 months after intraarticular Platelet rich plasma injectionTimepoint: 1Week,1Month,3Months,6Months,1Year—

Secondary

MeasureTime frame
To Standardised The Quantity, Dosing, Volume Of PrpTimepoint: 1Week,1Month,3Months,6Months,1Year—

Countries

India

Contacts

Public ContactDr Yatharth Ranjan

RG Kar Medical College And Hospital

sanjayorth@yahoo.co.in9163846467

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Apr 4, 2026