Which drug works better for pain relief after a Caesarean section dexmedetomidine or dexamethasone when added to a numbing medicine called levobupivacaine using an ultrasound guided injection

Comparative study on efficacy of ultrasound guided transversus abdominis plane block using dexmedetomidine versus dexamethasone as adjuvant to levobupivacaine for post-operative analgesia following caesarean section under sub arachnoid block. - NIL

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/02/105056

Enrollment

Registered

2026-02-27

Start date

Unknown

Completion date

Unknown

Last updated

2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Transversus abdominis plane block: After cesarean section TAP block will be given using ultrasonography after the closure of the skin. A high frequency linear probe (6-13 MHz) will be u

Eligibility

Inclusion criteria

Inclusion criteria: 1.ASA 2 2.Age 18 years to 45 years. 3.BMI less than or equal to 30 4.Patients able to understand and rate their pain in Visual Analogue Score

Exclusion criteria

Exclusion criteria: 1.Coagulopathy or patients on anticoagulation therapy. 2.History of allergy to Levobupivacaine, dexmedetomidine and dexamethasone. 3.Infection at the site of injection. 4.History of psychiatric illness. 5.History of significant heart disease, liver disease, renal disease, hypertension and diabetes mellitus.

Design outcomes

Primary

Measure	Time frame
To assess and compare efficacy of post operative pain relief in both groups.Timepoint: Till 24 hours post operative period.	—

Secondary

Measure	Time frame
To record the duration of post operative analgesia of block which is determined by time to first additional rescue analgesic administration. Total amount of additional analgesic consumption. To study side effects like nausea and vomiting and sedation.Timepoint: Till 24 hours post operative period.	—

Countries

India

Contacts

Public ContactShiv Kumar Singh

School of Medical Sciences and Research Sharda University

shiv.singh@sharda.ac.in9650943359

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Apr 4, 2026