A clinical study to compare a new chlorophyllin based gel with chlorhexidine gel as an additional treatment for patients suffering with gum disease

Clinical evaluation of a novel sodium copper chlorophyllin loaded cubosomal in situ gel compared to chlorhexidine gel as an adjunct to scaling and root planing in the treatment of stage 2 grade A periodontitis: a randomized controlled clinical trial - NIL

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/02/105012

Enrollment

Registered

2026-02-27

Start date

Unknown

Completion date

Unknown

Last updated

2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis

Interventions

Intervention1: Sodium copper chlorophyllin loaded cubosomal in situ gel: Participants in the test group will receive full mouth ultrasonic scaling and root planing followed by subgingival delivery of

Eligibility

Inclusion criteria

Inclusion criteria: untreaded stage 2 grade A periodontitis probing depth less than 5mm with bleeding on probing minimum 20 natural teeth present systemically healthy individuals willing to provide informed consent

Exclusion criteria

Exclusion criteria: pregnant or lactating women medically compromised patients periodontal therapy within the last 6 months smokers and former smokers known allergy to study materials

Design outcomes

Primary

Measure	Time frame
change in pocket probing depth from baseline to 14 daysTimepoint: Baseline 7 days 14 days	—

Secondary

Measure	Time frame
change in gingival index Loe and Silness from baseline to 14 daysTimepoint: baseline 7 days 4 days	—

Countries

India

Contacts

Public ContactDr Prisha Sumedha Reddy Sarella

KLE VK Institute of dental sciences

neelushetti1@gmail.com7799213283

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Apr 4, 2026