FindTrial
Sign In

A Study to Evaluate the Effect of Licorice Chewing Gum on Inflamed Gums, Dental Plaque, and Tooth Decay-Causing Bacteria among College Students with Gum Disease

The Efficacy of Licorice Chewing Gum against Dental Plaque, Gingivitis and Streptococcus mutans count A Double blind, randomized controlled trial - LIC-GUM Trial

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/02/104996
Enrollment
104
Registered
2026-02-27
Start date
Unknown
Completion date
Unknown
Last updated
2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K051- Chronic gingivitis

Interventions

Intervention1: Licorice Chewing Gum: Licorice extract as the active ingredient experimental gum. Control Intervention1: XYLITOL CHEWING GUM: 100% XYLITOL INFUSED CHEWING GUM Control Intervention2: Xyl

Sponsors

DR HARI SHANKAR S
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Participants aged 18-24 years Subjects having gingivitis Both male and female are included. Free from systemic diseases Subjects willing to offer informed consent & comply with research protocol

Exclusion criteria

Exclusion criteria: Subjects who have received antibiotics 3 weeks prior to the study. Subjects using other oral hygiene aids like Mouthwash, dental floss. Participants with deleterious habits such as smoking Participants with removable or fixed appliances Participants with a known history of allergy to any licorice/xylitol/gum base products

Design outcomes

Primary

MeasureTime frame
Reduction in dental plaque and gingival inflammation by Silness and L e Plaque Index and Loe and silness Gingival IndexTimepoint: baseline day0, day14,day21—

Secondary

MeasureTime frame
Reduction in salivary Streptococcus mutans count measured by colony-forming units per millilitre (CFU/mL).Timepoint: baseline day0, day21—

Countries

India

Contacts

Public ContactDR R PALANIVEL PANDIAN

BEST DENTAL SCIENCE COLLEGE

dentist.premkumar@gmail.com9042438114

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Apr 4, 2026