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ANTIMICROBIAL EFFICACY AND POST OPERATIVE PAIN FOLLOWED BY LASER ACTIVATED IRRIGATION AFTER A SINGLE VISIT ROOT CANAL THERAPY IN TEETH WITH PULPAL NECROSIS- A RANDOMISED CONTROLLED TRIAL

Antimicrobial efficacy and post operative pain following laser activated irrigation after a single visit root canal therapy in teeth with pulpal necrosis- A randomised controlled trial - nil

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/02/104988
Enrollment
50
Registered
2026-02-27
Start date
Unknown
Completion date
Unknown
Last updated
2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Laser and passive ultrasonic irrigation: EVALUATION OF ANTIMICROBIAL EFFICACY AND POST OPERATIVE PAIN FOLLOWING LASER ACTIVATED IRRIGATION AFTER A SINGLE VISIT ROOT CANAL THERAPY IN TE

Sponsors

Kushali R
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Systemically healthy patients (ASA 1) under the age group of 18- 65 years with a preoperative pain score ranging more than 5 cm on the VAS scale eliciting pain requiring primary root canal treatment in pulpal necrosis in mandibular molars are only considered

Exclusion criteria

Exclusion criteria: Teeth with crown or root fracture, periapical cyst, resorption defects, calcifications, aberrant anatomy, sinus opening, sealer extrusion and previous evidence of endodontic treatment

Design outcomes

Primary

MeasureTime frame
1. Reduction in bacterial load 2. VAS scoreTimepoint: 6hrs, 8hrs, 12hrs, 24hrs, 48hrs and 72hrs

Secondary

MeasureTime frame
post operative pain scoreTimepoint: At 6, 8, 12, 24, 48 and 72 hours after obturation;Post operative pain assessmentTimepoint: At 6, 8, 12, 24, 48, 72 hours

Countries

India

Contacts

Public ContactSathish Sundar

Meenakshi Ammal Dental College and Hospital

sathsundar87@gmail.com9884511763

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Apr 4, 2026