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Plasma IL-6 Levels as a Biomarker for Assessing Severity of Sepsis Using NEWS 2 Score in ICU Patients A Prospective Cohort Study

A Prospective Cohort Study to Evaluate the Association Between Plasma Interleukin-6 Levels and Severity of Sepsis Assessed by National Early Warning Score (NEWS) 2 in Patients Admitted to ICU at a Tertiary Care Hospital - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2026/02/104955
Enrollment
72
Registered
2026-02-26
Start date
Unknown
Completion date
Unknown
Last updated
2026-03-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: A419- Sepsis, unspecified organism

Interventions

Intervention1: NIL: NIL Intervention2: Nil: This is an observational study. No therapeutic intervention will be administered. Plasma IL 6 levels will be measured at ICU admission along with routine in

Sponsors

JAWAHARLAL NEHRU MEDICAL COLLEGE
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients aged 18 years and above diagnosed with sepsis as per Sepsis 3 criteria and admitted to ICU who provide informed consent.

Exclusion criteria

Exclusion criteria: Patients below 18 years, patients on immunosuppressive therapy, patients with malignancy, chronic inflammatory disorders, and those who refuse consent.

Design outcomes

Primary

MeasureTime frame
Correlation between plasma Interleukin 6 levels and severity of sepsis assessed by National Early Warning Score 2Timepoint: At time of icu admission At 48 hrs from admission—

Secondary

MeasureTime frame
Association of plasma Interleukin 6 levels with ICU mortalityTimepoint: During ICU stay until discharge or death;Association of plasma Interleukin 6 levels with requirement of mechanical ventilationTimepoint: During ICU stay;Association of plasma Interleukin 6 levels with length of ICU stayTimepoint: At ICU discharge;Association of plasma Interleukin 6 levels with need of vasopressors supportTimepoint: During ICU Stay—

Countries

India

Contacts

Public ContactDr Himanshu Bobade

Jawaharlal Nehru Medical college, Belagavi

rajubadiger@yahoo.com95904 73440

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Mar 14, 2026