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A Study of the Gut Bacterial Ecosystem in Indian Adults with Metabolic Syndrome.

A Cross-Sectional study to analyze the composition of Gut Microbiome in Indian individuals 18-60 years of age with Metabolic Syndrome in a Tertiary Care Center. - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2026/02/104868
Enrollment
50
Registered
2026-02-26
Start date
Unknown
Completion date
Unknown
Last updated
2026-03-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: E118- Type 2 diabetes mellitus with unspecified complications Health Condition 2: I10- Essential (primary) hypertension Health Condition 3: E669- Obesity, unspecified Health Condition 4: E88- Other and unspecified metabolic disorders

Interventions

Intervention1: Nil: Nil Intervention2: Nil: Nil

Sponsors

Jawaharlal Nehru Medical College
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Adults 18-60 years of age consenting to participate in the study. 2. Individuals meeting the NCEP ATP III Criteria for metabolic syndrome.

Exclusion criteria

Exclusion criteria: (i) any history of concurrent acute medical illness (ii) any symptoms pertaining to gastrointestinal (GI) disease (nausea/vomiting/pain in abdomen/diarrhea/blood in stool) (iii) any history of chronic illness (heart disease/kidney disease/liver disease/malignancy) (iv) any history in the past 3 months of intake of antibiotics/antifungals/antivirals (v) any history of consumption of illicit drugs within preceding six months (vi) any history of chronic GI diseases (IBD/inflammatory bowel syndrome (IBS)/chronic constipation/chronic diarrhea/abdominal tuberculosis) (vii) any history of GI malignancy or strong family history of colorectal cancer (viii) any history of other chronic illnesses such as autoimmune disease (multiple sclerosis/connective tissue disorders) or atopic disease (moderate severe asthma, eczema, eosinophilic disorders of the GIT), or moderate to severe undernutrition/malnutrition. (ix) Any pregnant or lactating women.

Design outcomes

Primary

MeasureTime frame
Gut Microbiota composition and diversityTimepoint: At the time of sample collection, i.e. baseline.—

Secondary

MeasureTime frame
identify specific microbial strains playing a role in the development of insulin resistanceTimepoint: At enrollment.;Comparison of gut microbial dysbiosis with fasting insulin levelsTimepoint: At enrollment—

Countries

India

Contacts

Public ContactEbrahim Ezzy

KLE Academy of Higher Education & Research

wiseman2380@yahoo.com9738462380

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Mar 14, 2026