Comparing Three Treatments (CEM Cement, MTA, and Simvastatin) to Help an Exposed Tooth Nerve Heal A Clinical Study.

EVALUATING THE EFFICACY OF CALCIUM ENRICHED MIXTURE (CEM) CEMENT, MTA, SIMVASTATIN AS DIRECT PULP CAPPING AGENTS A RANDOMIZED CLINICAL TRIAL. - NIL

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/02/104853

Enrollment

Registered

2026-02-26

Start date

Unknown

Completion date

Unknown

Last updated

2026-03-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Calcium Enriched Mixture Cement: CEM cement (Bionique Dent, Tehran, Iran) Total Duration - 12 months Intervention2: Simvatatin: 1.5 mg of simvastatin (Sigma-Aldrich, St. Louis, MO, USA)

Eligibility

Inclusion criteria

Inclusion criteria: Permanent teeth with a reversible pulpitis, Vital teeth, No history of spontaneous pain or Pain on percussion (POP) with a carious tooth, Periapical index score (PAI) of 1

Exclusion criteria

Exclusion criteria: Permanent teeth with Periapical pathosis, Non-vital teeth, Non-restorable teeth, Fractured teeth, and symptoms of irreversible pulpitis, Pregnant patients, Teeth exhibiting tenderness on palpation and percussion, Teeth with immature roots,and pathological mobility

Design outcomes

Primary

Measure	Time frame
Positive response to vitality tests, absence of clinical signs and symptoms, and PAI score 1Timepoint: 1,3,6, and 12 months follow-up	—

Secondary

Measure	Time frame
NilTimepoint: Nil	—

Countries

India

Contacts

Public ContactMANGAIYARKKARASI R A

RVS Dental college Hospital

drsibiswamy@gmail.com7811808888

Outcome results