None listed
Conditions
Interventions
Intervention1: IONTOPHORESIS AND INFERIOR ALVEOLAR NERVE BLOCK: Participants allocated to the experimental group will receive a conventional inferior alveolar nerve block using the same anaesthetic so
Sponsors
Dr Anuriti Guha
Eligibility
Inclusion criteria
Inclusion criteria: Healthy male and female patients classified as American Society of Anaesthesiologists (ASA) Class I; Patients aged 18 65 years; Presence of a mandibular first or second molar with clinical signs and/or symptoms suggestive of symptomatic irreversible pulpitis; Teeth showing positive exaggerated lingering response to pulp vitality testing (cold/ heat/ electric pulp testing); Presence of moderate to severe pre-operative pain consistent with irreversible pulpitis; Indicated for primary root canal therapy; Achievement of subjective lip numbness following administration of inferior alveolar nerve block (IANB) before study evaluation; Patients who can understand and use the Numerical Rating Scale for pain assessment; Patients who were willing to participate and provide written informed consent.
Exclusion criteria
Exclusion criteria: Pregnant women, patients who took analgesics or other medications that would change the inflammatory response of the pulp or provide analgesia 24 hr preoperatively; Individuals with known sensitivity to the pharmaceuticals or drugs to be used in the study ;Patients with systemic diseases and cardiac problems and pacemakers; Periodontal probing more than 3 mm associated with the tooth to be treated ;Nonvital teeth;Radiographic findings showing periapical changes;Patients not willing to participate in the study ;Third molars;Preendodontic build-up and rubber dam placement are not possible
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary outcome was the intensity of intraoperative pain experienced during endodontic access cavity preparation and instrumentation of canal, measured using the NRS, a 10cm continuous scale from 0 (no pain) to 10 (worst imaginable pain). The measure of analysis for each subject was the final pain score recorded at the time of pulp chamber entry after anesthesia administrationTimepoint: On the day of the procedure during access opening and instrumentation of canal | — |
Secondary
| Measure | Time frame |
|---|---|
| To assess gender predilection & compare anaesthetic efficacy & intraoperative pain perception between male & female patients ;To evaluate the influence of tooth type (mandibular first molar vs mandibular second molar) on the success of anaesthesia using standard IANB & IANB supplemented by iontophoresis ; To evaluate & compare the frequency, type (intraligamentary, intraosseous, intrapulpal, or buccal infiltration), & number of supplementary anaesthetic injections required in both study groups for successful completion of endodontic treatment. Timepoint: on the day of the treatment during access opening & pulp extirpation with no follow ups. | — |
Countries
India
Contacts
Public ContactDr. Manuel S Thomas
Manipal College of Dental Sciences , Mangalore
Outcome results
None listed