A research study comparing umbilical cord clamping at 1 minute versus 2 minutes after birth and its effect on red blood cell mass in growth restricted babies born at or after 28 weeks of gestational age

Effect of cord clamping at 120 10 seconds vs 60 10 seconds on postnatal haematological status among neonates more than or equal to 28 weeks gestation with estimated fetal weight less than 10th centile: A parallel group randomized controlled trial - NIL

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/02/104823

Enrollment

168

Registered

2026-02-26

Start date

Unknown

Completion date

Unknown

Last updated

2026-03-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Umbilical cord clamping: Umbilical cord clamping at 2 minutes of post-natal age Control Intervention1: Umbilical cord clamping: Umbilical cord clamping at 1 minutes of post-natal age

Eligibility

Inclusion criteria

Inclusion criteria: Neonates of gestational age more than 28 weeks to 42 weeks of gestation with estimated fetal weight less than 10th percentile for gestation by ultrasound

Exclusion criteria

Exclusion criteria: Neonates born to mothers with hemodynamic instability, placenta previa/abruptio placentae Multi fetal gestation Major congenital malformation Fetal hydrops Requiring resuscitation at birth Maternal isoimmunization

Design outcomes

Primary

Measure	Time frame
HematocritTimepoint: At 48 Hours of life	—

Secondary

Measure	Time frame
Incidence of polycythemiaTimepoint: At 48 hours of life;Polycythemia requiring partial exchangeTimepoint: At 48 hours of life;Vital parameters (Heart Rate, Mean arterial pressure, Respiratory rate, Temperature)Timepoint: At 1 & 2 hours of birth;Incidence of Neonatal Hyperbilirubinemia requiring phototherapy or exchange transfusionTimepoint: Within 72 hours of birth;Serum ferritinTimepoint: At 6 weeks of post-natal age;Incidence of PPH in motherTimepoint: Within 24 hours of delivery	—

Measure

Time frame

Incidence of polycythemiaTimepoint: At 48 hours of life;Polycythemia requiring partial exchangeTimepoint: At 48 hours of life;Vital parameters (Heart Rate, Mean arterial pressure, Respiratory rate, Temperature)Timepoint: At 1 & 2 hours of birth;Incidence of Neonatal Hyperbilirubinemia requiring phototherapy or exchange transfusionTimepoint: Within 72 hours of birth;Serum ferritinTimepoint: At 6 weeks of post-natal age;Incidence of PPH in motherTimepoint: Within 24 hours of delivery

—

Countries

India

Contacts

Public ContactDr. Bhabesh Kant Chowdhry

AIIMS Patna

drbhabeshkc@aiimspatna.org7871592369

Outcome results