Health Condition 1: N179- Acute kidney failure, unspecified
Conditions
Interventions
Intervention1: Nil: Nil
Sponsors
AIIMS,New Delhi
Eligibility
Inclusion criteria
Inclusion criteria: 1. Adult patients aged 18 to 60 years. 2. Thermal or scald burns involving 20 60% Total Body Surface Area (TBSA). 3. Admission to the Burn ICU within 48 hours of burn injury. 4. Presence of indwelling Foley s catheter for urine output monitoring (as per standard care). 5. Provision of informed written consent by the patient or legally authorized representative.
Exclusion criteria
Exclusion criteria: 1. Pre-existing renal disease or history of chronic kidney disease (CKD) (baseline creatinine greater than 1.5 mg/dL or known abnormal renal ultrasound). 2. Pre-existing bladder pathology such as neurogenic bladder, vesicoureteral reflux, bladder outlet obstruction, or recent urological procedures. 3. Abdominal surgery within the past 7 days prior to enrollment. 4. Pregnant women. 5. Patients with electrical burns exceeding 60 percentage TBSA or associated crush injuries. 6. Patients who decline consent or withdraw participation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Development of AKI as defined by KDIGO 2012 criteria during ICU stay. Timepoint: Baseline and every 24 hours till Day 5 or ICU discharge, whichever is earlier. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Determine IAP threshold predicting AKI Timepoint: At baseline and daily up to Day 5 or ICU discharge ;Assess Abdominal perfusion pressure(APP) and Renal Replacement Therapy (RRT) requirement Timepoint: Daily up to Day 5 or ICU discharge ;Correlation between abdominal girth and IAP Timepoint: Every 12 hours up to Day 5 ;IAP trends and fluid resuscitation Timepoint: During first 5 days of ICU stay ;Association of IAP with ICU outcomes (Length of stay,ventilation, mortality) Timepoint: At ICU discharge or death | — |
Countries
India
Contacts
Public ContactDr Surabhi Gupta
AIIMS,New Delhi
Outcome results
None listed