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Caffeine vs aminophylline which helps patients wake up faster after anesthesia

Comparing effects of caffeine and aminophylline on bispectral guided recovery of total intravenous anesthesia for spine surgeries a randomized control trial - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/02/104770
Enrollment
60
Registered
2026-02-25
Start date
Unknown
Completion date
Unknown
Last updated
2026-03-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M959- Acquired deformity of musculoskeletal system, unspecified Health Condition 2: O- Medical and Surgical Health Condition 3: M435- Other recurrent vertebral dislocation Health Condition 4: M958- Other specified acquired deformities of musculoskeletal system

Interventions

Intervention1: Caffeine Citrate and Aminophylline: Caffeine citrate is a CNS stimulant and reverses anaesthetic induced sedation by increasing central respiratory drive whereas Aminophylline causes ad

Sponsors

Dr Ria Handa
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA Physical status 1 and 2 and patients undergoing thoracolumbar spinal surgery with GCS of 15

Exclusion criteria

Exclusion criteria: Patients with concurrent cardiac disease, renal dysfunction, history of epilepsy, and hypersesitivity to theophylline or ethylenediamine

Design outcomes

Primary

MeasureTime frame
The primary outcome of the study is to assess and compare the ase of the return of consciousness after general anaesthesia after adminstering caffeine citrate and aminophylline in patients undergoing spinal surgeriesTimepoint: The recovery of patient from anaesthesia with be recorded and timed immediately

Secondary

MeasureTime frame
NILTimepoint: NIL

Countries

India

Contacts

Public ContactDr Mahantesh Mudakangoudar

KLEs Dr. Prabhkar Kore Academy of higher education and research

drmontygoudar@yahoo.co.in7829164500

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Mar 14, 2026