Health Condition 1: C509- Malignant neoplasm of breast of unspecified site
Conditions
Interventions
Intervention1: Nil: Nil
Sponsors
All India Institute of Medical Sciences Bhopal
Eligibility
Inclusion criteria
Inclusion criteria: 1. Age more than 30 years and less than 65 years. 2. ASAI/II patients. 3. Patients undergoing elective breast cancer surgery following neoadjuvant chemotherapy.
Exclusion criteria
Exclusion criteria: 1. Less than 30 years age. 2. Male breast cancer patients. 3. Patients apart from breast cancers. 4. Patient with pre-existing (before diagnosis of cancer) history of sleep disturbance or hereditary sleep disturbance. 5. Patient with advance cardio-pulmonary compromise (NYHA class 4). 6. Patients with history of psychiatric illness mainly Schizophrenia or other psychosis or neurosis. 7. Patient unable to communicate or understand the assessment tools. 8. BMI more than 30. 9. Uncontrolled diabetic and hypertensive patients. 10. Patients receiving exogenous thyroid supplements or antithyroid medications. 11. ASA grade III and IV. 12. Major blood loss during surgery- more than maximum allowable blood loss (MABL) i.e.65 ml/kg of ideal body weight. 13. Missing data on study variables. 14. Patients refusing informed consent. 15. Patients receiving medications known to interfere with hormonal response to stress (e.g. Beta blockers, steroids etc).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Measurement of Serum Cortisol, CRP and RBS.Timepoint: 8PM previous day 8 AM in the morning 2 hours after induction of anesthesia 24 hours post surgery. | — |
Secondary
| Measure | Time frame |
|---|---|
| IVCCI as a determinant of intravascular volume status.Timepoint: 8AM in the morning.;Sleep score of the patientTimepoint: Average reading of 3 preoperative days. | — |
Countries
India
Contacts
Public ContactDr Anuj Jain
All India Institute of Medical Sciences Bhopal
Outcome results
None listed