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Study of treatment outcomes and relapse patterns in patients with Ewingâ??s sarcoma involving the brain or spinal cord coverings.

Ewingâ??sSarcoma with Intradural Involvement: An Ambispective Study - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2026/02/104742
Enrollment
680
Registered
2026-02-25
Start date
Unknown
Completion date
Unknown
Last updated
2026-06-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C419- Malignant neoplasm of bone and articular cartilage, unspecified

Interventions

Intervention1: Nil: Nil Intervention2: Nil: Nil

Sponsors

TATA MEMORIAL HOSPITAL
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Patients diagnosed with histologically proven Ewingâ??s sarcoma of the dura, and vertebral/paravertebral/Chest wall/calvarial/skull base with intradural extension 2.Treated with radical intent at TMH/ACTREC from January 2013 to December 2030 (Partly treated in TMH/ACTREC or treatment advised from here) 3.Any age 4.With at least 6 months of follow-up

Exclusion criteria

Exclusion criteria: 1.Patients treated with palliative intent 2.Less than 6 months of follow-up 3.Referred outside or defaulted for treatment

Design outcomes

Primary

MeasureTime frame
To assess patterns of failure in patients with meningeal Ewingâ??s sarcoma either and patients with ewings sarcoma secondarily involvings the meninges.Timepoint: after completion of treatment during follow-up every 3 months for first 2 to3 years, every 6 months for next 2 years, and annually thereafter up to 5 years.

Secondary

MeasureTime frame
1.To assess outcomes [Local control (LC), Local Relapse Free Survival (LRFS), Disease Free Survival (DFS), Overall Survival (OS) in patients with meningeal sarcoma 2.To assess the relevance of systemic staging using FDG PET CECT 3.To assess prognostic factors for relapse 4.To compare LC, LRFS, DFS, OS & patterns of failure with vertebral/paravertebral/chestwall/calvarial/skull baseEwingâ??s sarcoma with intradural extension (secondary involvement) Timepoint: At baseline,after completion of treatment; during follow-up every 3 months for first 2to3 years, every 6 months for next 2 years & annually thereafter up to 5 years.

Countries

India

Contacts

Public ContactDr Jifmi Jose Manjali

Tata Memorial Hospital

jifmijosemanjali@gmail.com7045714838

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Jun 29, 2026