Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: 0.5% Propofol: 1 ml 1% Propofol diluted with 1ml 5% Dextrose final concentration: 5 mg/mL
patients will received 0.5% propofol Intravenously in a syringe pump at 99ml/hour until loss of
Sponsors
DrBabasaheb ambedkar medical college and hospital
Eligibility
Inclusion criteria
Inclusion criteria: 1.Female patients aged 18-45 years. 2.Scheduled for laparoscopic tubal ligation under general anaesthesia. 3.ASA physical status I or II. 4.Body Mass Index (BMI) 18 30 kg/m .
Exclusion criteria
Exclusion criteria: 1.Known allergy to propofol, egg, or soy products. 2.Cardiovascular disease: uncontrolled hypertension, arrhythmias, ischemic heart disease. 3.Respiratory disease: severe asthma, COPD. 4.Hepatic or renal dysfunction. 5.History of difficult airway or anticipated airway problems. 6.Patients on medications that interfere with anesthetic drugs (e.g., chronic sedatives, anticonvulsants). 7.Any neurological or psychiatric disorder affecting assessment of consciousness
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Time of beginning of infusion to time to loss of verbal response will be induction time(min)Timepoint: 3 months | — |
Secondary
| Measure | Time frame |
|---|---|
| Hemodynamic changes like systolic & diastolic blood pressure, heart rate, respiratory rate, pulse oximetry, endtidal- carbon dioxide will be recorded before induction, at the end of induction & 5 minutes after induction. Any Episodes of apnea will be noted,apnea is defined as observation of a cessation of breathing (10 or more seconds) by the patient,which is confirmed using capnography Total dose of propofol required for induction recorded (mg/kg) Injection pain will be assessed at the start of propofol administration using a Visual Analog Scale (VAS 0 10).Timepoint: 3 months | — |
Countries
India
Contacts
Public ContactDr Neetu Chaudhary
Dr.Baba Saheb Ambedkar Medical Collage And Hospital,Rohini,New Delhi
Outcome results
None listed