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Placental Gel and Hyaluronic Acid for Periodontitis

COMPARATIVE EVALUATION OF PLACENTAL GEL AND 0.2 PERCENTAGE HYALURONIC ACID GEL AS ADJUNCT TO SCALING AND ROOT PLANING IN TREATMENT OF CHRONIC PERIODONTITIS PATIENTS A SPLIT MOUTH RANDOMIZED CLINICAL TRIAL - NIL

Status
Active, not recruiting
Phases
Phase 3Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/02/104675
Enrollment
28
Registered
2026-02-24
Start date
Unknown
Completion date
Unknown
Last updated
2026-03-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis

Interventions

Intervention1: Placental gel: 14 sites in patients undergoing scaling and root planing will be administered with placental extract gel (PLACENTREX Gel, Albert David) adsorbed in a resorbable collagen

Sponsors

Dr PULLALAREVU DIVYA SAI
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Subjects having a minimum 20 teeth. Subjects with chronic periodontitis with probing depth greater than or equal to 5mm, clinical attachment level greater than or equal to 1mm.

Exclusion criteria

Exclusion criteria: Patients with any systemic diseases. Patients who have undergone anti-microbial therapy in the past 6 months. Patients who have undergone periodontal therapy in the past 6 months. Pregnant and Lactating women. Smokers and Tobacco users. Patients who are allergic to placental gel and hyaluronic acid gel.

Design outcomes

Primary

MeasureTime frame
Probing depth and Clinical attachment level Will be assessed using UNC 15 Probe Probing depth will be assessed from Gingival margin to the base of the pocket Clinical Attachment Level will be assessed from Cementoenamel Junction to the base of the pocket Timepoint: baseline, 6 weeks and 3 months

Secondary

MeasureTime frame
Gingival Index (GI) (Loe H, Silness J) 1963 Plaque Index (PI) (Silness J, Loe H) 1964 Timepoint: baseline, 6 weeks and 3 months

Countries

India

Contacts

Public ContactPULLALAREVU DIVYA SAI

Sri Rajiv Gandhi College of Dental Sciences and Hospital

umeshyadalam@gmail.com9844269511

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Mar 14, 2026