Health Condition 1: J449- Chronic obstructive pulmonary disease, unspecified
Conditions
Interventions
Intervention1: Glycopyrronium and indacetrol fixed dose combination once daily in moderate to severe chronic obstructive pulmonary disease patients: Glycopyrronium 50 mcg and indacetrol 110 mcg fixe
Sponsors
Department of chest and Tb university of health sciences vallah amritsar punjab
Eligibility
Inclusion criteria
Inclusion criteria: Patients aged more than 18 years non smaokers or ex smokers and had a diagnosis of chronic obstructive and pulmonary diseases with presence of respiratory symptoms postbronchodilator forced expiratory volume in one second divided by forced vital capacity ratio of less than 70 percentage and postbronchodilator forced expiratory volume more than equal to 30 percentage and less than 80 percentage of predicted
Exclusion criteria
Exclusion criteria: Pregnant and or lactating mothers. Patients with diagnosis of asthma. Known underlying cardiovascular abnormalities like arrhythmias, congestive heart failure, coronary heart disease. Patients with history of hospitalization for pneumonia within 3 months of enrolment. Patients with history of use of oral or parentral corticosteroid or depot corticosteroid use 6 weeks before the enrolment. Contraindications or hypersensitivity to any of the study drugs. Suspected presence of active TB and other communicable diseases. Patients with neurological , musculoskeletal and peripheral vascular diseases. Active hemoptysis is also contraindication
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To help better access of superior inhaler combination among glycopyrronium and indacetrol fixed dose combination versus tiotropium and formetrol fixed dose combination in patients with moderate to severe chronic obstructive pulmonary diseaseTimepoint: Time points will be at baseline 6 weeks and then at 12 weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| NilTimepoint: Nil | — |
Countries
India
Contacts
Public ContactDr Sunil Grover
Sri Guru Ram Das University of Health Sciences
Outcome results
None listed