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A study on the effect of hyaluronic acid gel on wound healing after gum surgery

Effect of hyaluronic acid on wound healing in Free Gingival Graft (FGG) and estimation of Transforming Growth Factor Beta-1(TGF B1)levels in palatal wound fluid -A Randomised controlled clinical trial - NIL

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/02/104639
Enrollment
30
Registered
2026-02-24
Start date
Unknown
Completion date
Unknown
Last updated
2026-03-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: T788- Other adverse effects, not elsewhere classified

Interventions

Intervention1: Hyaluronic acid gel: cross linked hyaluronic acid gel , 1ml topical application on donor and 1 ml in topical application recepient site ,one time application Control Intervention1: NIL

Sponsors

Dr Haritha M
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Systemically healthy individuals Age ranging between 18 and 40 years Mucogingival problems indicating treatment by free gingival graft with no pathology or morphological alterations of palatal mucosa Miller s class two recession in anterior region Keratinized width less than two millimeter in at least one of four mandibular incisors

Exclusion criteria

Exclusion criteria: Caries or non carious cervical lesion at recipient sites Severely malpositioned teeth Teeth with residual probing depth more than four millimeter , mobility more than one millimeter Vertical bone loss,smokers,or former smokers Pregnant or lactating women Systemic disease or any other condition that impair gingival healing

Design outcomes

Primary

MeasureTime frame
Wound healing of donor site and recipient siteTimepoint: At baseline , 1 month ,3 month ,6 month post operatively

Secondary

MeasureTime frame
Transforming growth factor beta -1 levels in palatal wound fluid & visual analog scaleTimepoint: At 7 th day , 14 th day post operatively

Countries

India

Contacts

Public ContactDr. Haritha . M

Karpaga vinayaga institute of dental sciences

hemaarun21@gmail.com9884970030

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Mar 14, 2026