A reaearch to find out inj sugammadex works good for inj rocuronium or inj vecuronium in anaesthesia

Comparison of the efficacy and safety profile of sugammadex in the reversal of rocuronium and vecuronium induced neuromuscular blockade in patients undergoing general surgeries - A prospective randomised control trial - NIL

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/02/104629

Enrollment

Registered

2026-02-24

Start date

Unknown

Completion date

Unknown

Last updated

2026-03-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical Health Condition 2: O- Medical and Surgical

Interventions

Intervention1: Inj Sugammadex: To study the efficacy and safety profile of Sugammadex in the reversal of rocuronium and vecuronium induced neuromuscular blockade Control Intervention1: Inj Rocuronium:

Eligibility

Inclusion criteria

Inclusion criteria: ASA 1&2,18-60 years undergoing elective general surgeries like Modified radical mastectomy,Lap appendicectomy, thyroidectomy,Lap cholecystectomy under general anaesthesia,BMI <29 or equal to 29,MPG 1 and 2

Exclusion criteria

Exclusion criteria: ASA 3&4,BMI more than 29, neuromuscular disease, hepatic and renal disease, allergy to drug used, pregnancy and lactation, difficult airway ( MPG 3 & 4 )

Design outcomes

Primary

Measure	Time frame
To find out the time required to achieve a train of four ratio more than or equal to 0.9 after administration of sugammadex Timepoint: 1st postoperative day	—

Secondary

Measure	Time frame
1.To assess hemodynamic changes after reversal 2.To elicit the adverse events and complications 3.To evaluate the overall recovery profile and extubation time and compare with each other 4.To determine variation with regard to gender,age group and the quality of drugs used Timepoint: 1st postoperative day	—

Countries

India

Contacts

Public ContactDrVaishaliG

Government Rajaji Hospital and Madurai Medical College

dr.b.velmurugan@gmail.com9787714295

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Mar 14, 2026