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A study comparing two-hourly and three-hourly feeding in very low birthweight newborn babies to assess the time taken to reach full milk feeds

Comparison of 2-Hourly vs. 3-Hourly Feeding Schedule in Very Low Birth Weight Neonates:A Randomised Control Trial. - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/02/104609
Enrollment
110
Registered
2026-02-24
Start date
Unknown
Completion date
Unknown
Last updated
2026-03-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: P071- Other low birth weight newborn

Interventions

Intervention1: 3 hourly feeding in VLBW neonates: 3 hourly feeding schedule comparing 2 hourly feeding schedule in VLBW neonates in time to reach full enteral feed Control Intervention1: 2 hourly feed

Sponsors

Nil
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Hemodynamically stable neonates with a birth weight of 1000 g to 1499 g, in whom feeding is initiated within 96 hours

Exclusion criteria

Exclusion criteria: 1-Major congenital anomalies like tracheoesophageal fistula, esophageal atresia and duodenal atresia that can interfere or delay feed initiation. 2-Severe birth asphyxia (Apgar 0 to 3 at 5 minutes) 3-Very sick or shock neonates or requiring invasive mechanical ventilation. 4-Neonates with NEC at baseline. 5-Neonates with absent or reversed end diastolic flow (AEDF/REDF) in antenatal USG.

Design outcomes

Primary

MeasureTime frame
Time (in days) taken to reach full enteral feeds (150 ml/kg/day) in very low birthweight neonates.Timepoint: Time (in days) to reach full enteral feeds (150 ml/kg/day).

Secondary

MeasureTime frame
Incidence of feeding intolerance Occurrence of NEC Rate of weight gain & time to recover birth weight Hypoglycemia MortalityTimepoint: As secondary outcomes will be assessed based on primary outcomes which is time taken in days to reach full enteral feed. No specific time is predetermined because of variability

Countries

India

Contacts

Public ContactDr Shaique Azam

Dr Baba Saheb Ambedkar Medical College and Hospital

vimalnag2011@gmail.com7838007502

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Mar 14, 2026