Health Condition 1: T312- Burns involving 20-29% of body surface Health Condition 2: T312- Burns involving 20-29% of body surface
Conditions
Interventions
Intervention1: trenexamic acid: iv tranexamic acid 15mg/kg 10 mins prior to surgery given only once
Control Intervention1: isotonic saline: isotonic saline 10ml given 10 mins prior to surgery only onc
Sponsors
BANGALORE MEDICAL COLLEGE AND RESEARCH INSTITUTE
Eligibility
Inclusion criteria
Inclusion criteria: All males and females aged 18-60 yrs All patients with less than 30% deep dermal (2nd degree and above) burns Patient willing to give informed consent
Exclusion criteria
Exclusion criteria: Patients with coagulopathy Pregnancy Patients with chronic kidney disease Patients with allergy to tranexamic acid Acute venous or arterial thrombosis within 3 months of inclusion in the study Seizure disorder
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Blood loss in ml Amount of blood transfusion required Pre and post op hemoglobin and hematocrit Timepoint: blood loss assessed intra operatively amount of blood transfusion required on post op day 1 pre and post op hemoglobin and hematocrit on post op day 1 | — |
Secondary
| Measure | Time frame |
|---|---|
| Percentage of graft uptakeTimepoint: post op day5 7 and 14 | — |
Countries
India
Contacts
Public ContactDr PRASHALI CHAUHAN
BANGALORE MEDICAL COLLEGE AND RESEARCH INSTITUTE
Outcome results
None listed