A study of presence of a common mood disorder after cesarean delivery in mothers receiving anesthesia inform of spinal injection along with a port kept in back which can be used or pain relief or without it.

Comparison of spinal versus combined spinal-epidural anaesthesia on the incidence of postpartum blues in patients undergoing caesarean delivery: a randomized controlled trial - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/02/104560

Enrollment

120

Registered

2026-02-24

Start date

Unknown

Completion date

Unknown

Last updated

2026-03-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: F53- Puerperal psychosis

Interventions

Intervention1: Regional Anaesthesia technique: Combined Spinal epidural anaesthesia To be placed before surgery and epidural shall be left for pain medication till 3rd day in post op period Control I

Eligibility

Inclusion criteria

Inclusion criteria: Women aged between 18 40 years, undergoing caesarean delivery (Category III & IV LSCS) American Society of Anaesthesiologists (ASA) physical status I II Able to understand and complete study questionnaires (e.g. literate in local language)

Exclusion criteria

Exclusion criteria: Pre-existing psychiatric illness or current use of antidepressant or anxiolytic medication Contraindication to neuraxial anaesthesia (e.g. coagulopathy, infection at puncture site, severe spinal deformity) Severe obstetric complications (e.g. pre-eclampsia with severe features, eclampsia, HELLP syndrome) Multiple gestation Advanced cardiac disease Unwillingness to receive an epidural cathete (for the CSE group, if randomized)

Design outcomes

Primary

Measure	Time frame
Incidence of maternal blues on POD-3 using Edinburgh Postnatal Depression Scale (EPDS) in women undergoing caesarean deliveries under SA versus CSETimepoint: Assessed on post operative day 3	—

Secondary

Measure	Time frame
Severity of maternal blues using EPDS between SA and CSE in women undergoing caesarean deliveriesTimepoint: Assessed on Post operative day 3;Incidence of postpartum blues using EDPS score Timepoint: Assessed at 6 weeeks postpartum;Post-operative pain scores in both groups using NRS scoreTimepoint: Assessed at 6 hours, 24 hours, 48 hours, 72 hours after surgery	—

Countries

India

Contacts

Public ContactDr Choro Athiphro Kayina

AIIMS New Delhi

kayinaathiphro@gmail.com9654116228

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Mar 14, 2026