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Study to Detect Inherited High Cholesterol in Young Patients with Early Heart Disease

Establishment of a Screening Program for Familial Hypercholesterolemia along with Comprehensive Assessment of Novel Lipid Biomarkers and Evaluation of a Machine Learning Algorithm in Young Adult Patients Presenting with Premature Coronary Artery Disease to a Tertiary Care Hospital - FLASH

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2026/02/104559
Enrollment
500
Registered
2026-02-23
Start date
Unknown
Completion date
Unknown
Last updated
2026-03-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: I219- Acute myocardial infarction, unspecified Health Condition 2: I700- Atherosclerosis of aorta Health Condition 3: I708- Atherosclerosis of other arteries Health Condition 4: I251- Atherosclerotic heart disease of native coronary artery

Interventions

Intervention1: Nil: Nil

Sponsors

Christian Medical College Vellore
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Acute coronary syndromes (STEMI, NSTEMI, unstable angina) Stable ischemic heart disease Ischemic cerebrovascular accidents Peripheral arterial disease Coronary interventions (PCI or CABG) Coronary artery calcium score greater than 100

Exclusion criteria

Exclusion criteria: Non atherosclerotic CAD (coronary artery dissection etc.) Failure to provide consent

Design outcomes

Primary

MeasureTime frame
Establishment of a Screening Program for Familial Hypercholesterolemia (FH)Timepoint: Three years.—

Secondary

MeasureTime frame
Comprehensive Assessment of Novel Lipid BiomarkersTimepoint: Three years.;Evaluation of a Machine Learning Algorithm in Young Adult Patients Presenting with Premature Coronary Artery Disease to a Tertiary Care Hospital.Timepoint: Three years—

Countries

India

Contacts

Public ContactDr Aditya John Binu

Christian Medical College Vellore

adityabinu@gmail.com9940789083

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Mar 14, 2026