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Effect of Nebulized Ropivacaine and Lignocaine with Magnesium Sulphate in Controlling Stress Response During Intubation

COMPARISON OF NEBULIZED ROPIVACAINE (0.75%) AND MAGNESIUM SULPHATE WITH NEBULIZED LIGNOCAINE (2%) AND MAGNESIUM SULPHATE WITH CONTROLLED GROUP IN ATTENUATION OF HEMODYNAMIC RESPONSE DURING INTUBATION IN PATIENTS UNDERGOING ELECTIVE SURGERY UNDER GENERAL ANAESTHESIA: A PROSPECTIVE RANDOMISED CONTROLLED STUDY - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/02/104554
Enrollment
120
Registered
2026-02-23
Start date
Unknown
Completion date
Unknown
Last updated
2026-03-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Nebulization: 5ml of either Ropivacaine (0.75%) or lignocaine (2%) adding 2ml of Magnesium sulfate to both patient will be nebulized 15 minutes prior to intubation Control Intervention1

Sponsors

Bhopal memorial hospital and research center
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA- I or II, BMI- 18-30 kgm2 ,Gastrointestinal surgeries and Neurosurgery done under General anaesthesia

Exclusion criteria

Exclusion criteria: Patient refusal Patient with a recent history of sore throat or upper respiratory tract infection Patients with a history of allergy to local anesthetics Mallampati grade 3 & 4 Pregnant females

Design outcomes

Primary

MeasureTime frame
Objective of this study is to find out the changes in hemodynamic parameters between 3 groups at the time of intubationTimepoint: Objective of this study is to find out the changes in hemodynamic parameters between 3 groups at the time of intubation—

Secondary

MeasureTime frame
To evaluate for the complaint of post operative sore throatTimepoint: After extubation—

Countries

India

Contacts

Public ContactDr Kuldeep Hinsu

Bhopal memorial hospital and research center

saiftipu123@gmail.com9630044555

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Mar 14, 2026