FindTrial
Sign In

Study of Heart Chamber Function and Its Relation to Surgical Outcomes in Adults with Severe Aortic Valve Narrowing Undergoing Valve Replacement Surgery

Relationship of Left Atrial Systolic Force with Left Atrial Strain and other Left Atrial Functional Parameters and their Association with Perioperative Outcomes in Adult Patients with Aortic Stenosis Undergoing Surgical Aortic Valve Replacement(AVR) using Transesophageal Echocardiography(TEE): A Prospective Observational study - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2026/02/104413
Enrollment
53
Registered
2026-02-20
Start date
Unknown
Completion date
Unknown
Last updated
2026-03-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: I060- Rheumatic aortic stenosis

Interventions

Intervention1: Nil: Nil Intervention2: Nil: Nil Intervention3: Nil: Nil Intervention4: Nil: Nil

Sponsors

All India Institute of Medical Sciences
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Severe AS 2.Baseline sinus rhythm on ECG. 3.Normal LV function 4.Scheduled for surgical AVR. 5.Written informed consent

Exclusion criteria

Exclusion criteria: 1.Persistent or permanent atrial fibrillation/flutter/left bundle branch block/complete heart block or other arrhythmias precluding LA strain measurement. 2.More than mild mitral valve disease/more than mild AR or significant tricuspid/pulmonary valve disease. 3. Prior valve surgery or significant congenital heart disease or atrial septal defect or coarctation of aorta besides isolated AS. 4. Patients with LV dysfunction 5. Infective endocarditis or systemic infection/sepsis. 6. Poor TEE imaging window

Design outcomes

Primary

MeasureTime frame
Correlation of LAEF with LA strain and functional indices intraoperatively.Timepoint: 1. Baseline 2. Post Aortic valve replacement—

Secondary

MeasureTime frame
Perioperative MACE (mortality, MI, stroke, heart failure). Duration of mechanical ventilation. ICU stay length. Vasoactive support requirements. Postoperative atrial fibrillation incidence.Timepoint: Postoperative day 0, Post operative day 1 & postoperative day 2/until discharge from ICU—

Countries

India

Contacts

Public ContactDrishya P

All India Institute of Medical Sciences,, New Delhi

minati.2002@gmail.com7042981227

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Mar 14, 2026