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A study comparing 2 drugs - dexmedetomidine and magnesium sulphate for maintaining stable blood pressure and heart rate in patients undergoing functional endoscopic sinus surgery under general anaesthesia

Comparison of haemodynamic stability in patients receiving dexmedetomidine and magnesium sulphate in functional endoscopic sinus surgery under general anaesthesia - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2026/02/104393
Enrollment
33
Registered
2026-02-20
Start date
Unknown
Completion date
Unknown
Last updated
2026-03-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Nil: Nil Intervention2: Dexmedetomidine: intravenous dexmedetomidine loading dose of 0.5 g/kg over 10 minutes followed by infusion at a rate of 0.5 g/kg/hr Control Intervention1: Magn

Sponsors

Government Medical College Kozhikode
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients aged 18 to 60 years American Society of Anesthesiologists (ASA) physical status I or II Posted for elective FESS under general anesthesia

Exclusion criteria

Exclusion criteria: Known hypersensitivity to study drugs Patients having uncontrolled hypertension, cardiovascular diseases or cerebrovascular diseases Renal or hepatic impairment Pregnant or lactating women Patients on alpha 2 adrenergic agonists

Design outcomes

Primary

MeasureTime frame
Intraoperative blood pressure and heart rate Timepoint: baseline, after drug administration, post intubation, thereafter at intervals of 5 minutes till the end of surgery

Secondary

MeasureTime frame
1.Quality of the surgical field using an Intra Operative Surgical Field Evaluation scale (IOSFE) Boezaart Scale between two groups 2.Numeric Pain Rating Scale (NRS) for pain evaluation between two groups 3.Ramsay Sedation Scale for postoperative recovery time between two groupsTimepoint: 1)Quality of the surgical field using an Intra Operative Surgical Field Evaluation scale (IOSFE) Boezaart Scale at 15 minutes interval after starting surgery 2)Numeric Pain Rating Scale (NRS) at 1 hour 3 hours & 6 hours after extubation 3)Ramsay Sedation Scale at 1 hour 3 hours & 6 hours after extubation

Countries

India

Contacts

Public ContactDr KRISHNA DAS A

Government Medical College Kozhikode

drakrishnadas@gmail.com9447382969

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Mar 14, 2026