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A Study Comparing Two Sedation Drugs for Faster Recovery after ERCP procedure

Comparison between dexmedetomidine and remifentanil as adjuvant to propofol for postoperative recovery in patients undergoing ERCP under monitored anaesthesia care - NIL

Status
Active, not recruiting
Phases
Phase 3Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/02/104331
Enrollment
80
Registered
2026-02-19
Start date
Unknown
Completion date
Unknown
Last updated
2026-03-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Dexmedetomidine loading dose 1mcg/kg IV in 20ml 0.9% normal saline over 10 minutes: In group D,Dexmedetomidine loading dose 1mcg/kg IV in 20ml 0.9% normal saline over 10 minutes,then

Sponsors

DR SN Medical college Jodhpur Rajasthan
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: will include adult patients, aged 18 to 60 years and undergoing ERCP under Monitored anesthesia care who belongs to ASA PS I, II

Exclusion criteria

Exclusion criteria: 1.Patient refusal 2. History of any allergy to related medications 3.Patients with psychiatric history, myopathy, with neurological disease 4. Patients with kidney disease, ischemic, severe pulmonary and heart disorders 5.Active GI bleeding 6.Obesity (BMI greater than 30kg/m2) 7. Pregnant woman 8. Procedure time greater than 60 minutes

Design outcomes

Primary

MeasureTime frame
To compare quality of postoperative recovery from anaesthesia in terms of Richmond Agitation Sedation Scale in patients undergoing endoscopic retrograde cholangiopancreatography under monitored anaesthesia care with dexmedetomidine and remifentanil as adjuvants to propofol.Timepoint: 0min,5min,10min,15min,20min,30min,45min,60min

Secondary

MeasureTime frame
The following parameters will be compared between dexmedetomidine and remifentanil groups: Intraoperative and postoperative hemodynamic assessment Total propofol consumption Time to achieve MAS 9 or more Ramsay sedation score Postprocedural VAS score complications surgeon satisfaction using Gloucester score Patient satisfaction using Likert scoreTimepoint: T1 IS TIME AFTER PROPFOL LOADING DOSE THERAFTER EVERY 5MINS TILL SURGERY OVER

Countries

India

Contacts

Public ContactMeera Mohan

Dr SN Medical College, Department Of Anaestheisology,Jodhpur

chandakhatri90@gmail.com8619236716

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Mar 14, 2026