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A Study of Two Nerve Block (Intertransverse and Thoracic Paravertebral)for Pain Relief after Modified Radical Mastectomy Surgery

Comparing intertransverse process (ITP) block with thoracic paravertebral (TPV) block for postoperative analgesia in patient undergoing modified radical mastectomy (MRM); A randomized controlled non inferiority trial - NIL

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/02/104305
Enrollment
100
Registered
2026-02-19
Start date
Unknown
Completion date
Unknown
Last updated
2026-03-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C50- Malignant neoplasm of breast

Interventions

Intervention1: After induction and before incision admnistration of Inter transverse process(ITP) block and Thoracic paravertebral (TPV) block: Inter transverse process(ITP) block given in one group o

Sponsors

Dr Piyush Meena
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.ASA 1 and ASA 2 patients 2.Patient undergoing MRM under General Anaesthesia 3.Patient between 18 to 65 years of age 4.Patient who can understand and provide a valid consent for the procedure and can understand and are willing to report the pain using NRS score

Exclusion criteria

Exclusion criteria: 1.Patients not giving consent 2.Patient with allergies to Local anaesthetics 3.Patient having bleeding disorders 4.Patient on anticoagulant or antiplatelet drus 5.Localised infections 6.Patient in whom the sonoanatomy of the anaesthetiic injection site is clearly not delineable due to any reason 7.Patient with previous history of breast surgery 8.Patient on long term opioid therapy 9.Patient with peripheral neuropathy 10.INR more than 1.5

Design outcomes

Primary

MeasureTime frame
Assessment of the pain using NRS score at 24 hours postoperatively among both groupTimepoint: 24th hr

Secondary

MeasureTime frame
1.To observe the time needed for first rescue analgesia(IV Tramadol) 2.To compare the total number of dose of rescue analgesia required to achieve adequate analgesia 3.To compare intraoperative hemodynamic parameters(Heart rate,Mean arterial pressure,Systolic blood pressure,Diastolic blood pressure) 4.To compare intraoperative intravenous fentanyl consumption 5.To compare time taken to perform the blockTimepoint: intraoperative assessment at baseline parameters and 15,30,45,60,75,90,105,120 minutes intraoperatively and postoperative assessment at 30minute,1,2,6,12,24,48 hrs

Countries

India

Contacts

Public ContactProf Ghanshyam Yadav

Institute of Medical Sciences BHU

ghanshyambhu1976@gmail.com9838894169

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Mar 14, 2026