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The REAP stain approach to enhance cervical cytology

REAPING INNOVATION: THE REAP STAIN APPROACH TO ENHANCE CERVICAL CYTOLOGY - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2026/02/104262
Enrollment
185
Registered
2026-02-18
Start date
Unknown
Completion date
Unknown
Last updated
2026-03-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Nil: Nil

Sponsors

DEPARTMENT OF HEALTH RESEARCH, MINISTRY OF HEALTH AND FAMILY WELFARE
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Cervical smears collected from women undergoing standard gynaecological screenings. 2. Adequately fixed cervical smears.

Exclusion criteria

Exclusion criteria: 1. Inadequately fixed or poor-quality cervical smears. 2. Cervical smears with scanty cellularity.

Design outcomes

Primary

MeasureTime frame
Determine whether REAP staining provides comparable cytological detail and diagnostic clarity to the conventional Pap stain. Evaluate the turnaround time, cost per slide, and technical feasibility of implementing REAP in resource-constrained settings. Offer a practical staining protocol that could be adopted in high-volume or rural screening programs, where cost and time are limiting factors.Timepoint: T0 Immediately after staining (same day): Slide quality assessment (nuclear detail, cytoplasmic transparency, staining crispness, background clarity). T1 At the time of cytological reporting (within 24 48 hours): Diagnostic categorization using the The Bethesda System. T2 After independent blinded review (within 1 week): Interobserver agreement analysis (kappa statistics).

Secondary

MeasureTime frame
nilTimepoint: nil

Countries

India

Contacts

Public ContactDr Shruti Deshpande

Datta Meghe Medical College

drayachit@gmail.com9637795676

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Mar 14, 2026