Gel placement of a novel gel using Bifidobacterium breve which is a probiotic gel that is gel made from live beneficial organisms that will be used for the treatment of the gap which is present between gums and tooth

Assessing the efficacy of a probiotic gel containing Bifidobacterium breve NCIM 5671 in the treatment of periodontitis: A randomised controlled trial study - NIL

Status

Active, not recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/02/104232

Enrollment

Registered

2026-02-18

Start date

Unknown

Completion date

Unknown

Last updated

2026-03-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis

Interventions

Intervention1: Local drug delivery of probiotic Bifidobacterium breve gel: Local drug delivery of a 1% gel made from a probiotic for the treatment of periodontal pockets. Dose depending on the periodo

Eligibility

Inclusion criteria

Inclusion criteria: Probing pocket depth (PPD) of 4-6 mm as examined with Williams probe Clinical attachment level (CAL) of 1-5 mm as examined with William s probe Systemically healthy subjects

Exclusion criteria

Exclusion criteria: Patients with the history of periodontal therapy within 6 months prior to the study. Chronic use of antibiotics/ anti- inflammatory drugs 1 month prior to the study Routine use of mouthwash or other plaque controlling agents Diabetic patients or other immunocompromised patients Smokers Known history of allergic to drugs Pregnant and lactating women Aggressive periodontitis cases.

Design outcomes

Primary

Measure	Time frame
Probing Pocket Depth (PPD) Clinical attachment loss(CAL)Timepoint: Baseline, 1month, 3 month	—

Secondary

Measure	Time frame
Bleeding on Probing Plaque index Gingival IndexTimepoint: Baseline, 1month, 3 month	—

Countries

India

Contacts

Public ContactDr Shivanand S

JSS Dental College and Hospital

sumanbv_72@yahoo.co.in9945551564

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Mar 14, 2026